Dry Mouth is a common side effect of radiation or chemotherapy for cancer patients. Approximately 90-100% of head and neck cancer patients treated with radiation will develop oral complications, with Dry Mouth being the most common. It is important to take steps before and during treatment to protect against the discomfort and problems associated with Dry Mouth.

Dry Mouth can develop into mucositis if left untreated.  It is a debilitating complication of cancer treatments and can lead to several problems, including pain, the inability to eat, and an increased risk of infection due to open mouth sores. 

Patients have often used “saliva substitutes” as part of the prevention and treatment of cancer-related dry mouth. Aquoral can be an important addition to your Dry Mouth strategy, helping to prevent mucositis and positively impacting a patient’s quality of life while going through cancer treatment.

  • Unlike most over-the-counter water-based products, Aquoral’s lipid-based formulation lubricates and creates a protective barrier helping trap moisture in the oral mucosa and helping prevent cancer-related oral problems such as mucositis
  • Aquoral can be used alone as a single agent or in combination as a cost-effective way to “lock in” the moisturizing effects and prolong the benefit of other dry mouth treatments
  • Aquoral is available in a small lightweight spray that can be easily carried during daily activities

Here are a few additional steps you can take to help moisturize and protect your mouth during treatment:

  1. Stay hydrated: It’s important for cancer patients to drink plenty of water and other fluids to keep the mouth moist. Sipping water throughout the day is helpful.
  2. Avoid tobacco and alcohol: Both tobacco and alcohol can dry out the mouth and exacerbate the symptoms of Dry Mouth. It’s best to avoid them altogether.
  3. Choose moist foods: Eating moist foods such as soups, stews, and fruits can help to keep the mouth moist.
  4. Practice good oral hygiene: Brushing and flossing regularly can help prevent dental problems that can make Dry Mouth worse.
  5. Talk to your healthcare provider: If you are experiencing Dry Mouth, talk to your healthcare provider to see how Aquoral can become part of your treatment plan.

Get Relief From Dry Mouth - Aquoral is:


Lipid-based spray lubricates and provides a protective shield that helps the oral mucosa retain moisture


Helps prevent mucosal damage & tooth decay while improving the ability to chew, taste, swallow, and speak

Fast & Long-lasting

Two quick sprays provide rapid relief that lasts for 4 to 6 hours, and reduces the need for frequent dosing

Easy to Use

Small size fits in a pocket or purse; no need for mixing or frequent rinsing as with water-based formulations

best mouth spray for dry mouth
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Convenient Ordering

If you are having trouble finding Aquoral on your e-prescribing software, please use our Fax form.  

Get Aquoral

You are now leaving to obtain an online prescription in 3 easy steps:

  1. Create an account and answer a few intake questions
  2. Your information is reviewed by a licensed medical professional who will send it to the pharmacy for processing. The total charge is $99.
  3. Aquoral is shipped directly to you at no additional cost

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Intake review will take place within 24 hours. Standard shipping times apply – your prescription will arrive in 3-5 days. Select states may be subject to a video call.

Convenient Packaging

Over-the-counter Dry Mouth products are often sold in large bottles due to the frequency of use. Prescription supersaturated calcium phosphate rinses come in foil packets which need to be mixed in a large quantity of water before use.

Aquoral comes in two convenient 10 mL spray bottles that easily fit in a pocket, purse, or on a night table.

No Rinse and Repeat

Many non-prescription Dry Mouth treatments and prescription supersaturated calcium phosphate rinses require rinsing and spitting out and should not be swallowed.

Aquoral is a discreet, easy-to-use spray.


Aquoral’s formulation provides long-lasting relief. Finally, a solution that lubricates AND forms a protective layer that keeps moisture in the oral cavity.

Delivering sustainable relief for up to 6 hours.

Provides Relief

Most saliva substitutes hydrate and lubricate the oral mucosa providing temporary relief of Dry Mouth.

Aquoral’s OGT formulation creates a protective shield which, when used alone or combined with other Dry Mouth treatments, can lock in moisture, and enhance effectiveness.

What is Dry Mouth?

Dry Mouth is a more serious medical condition than its name would suggest. In most cases, patients’ daily lives and oral health can be significantly compromised if their Dry Mouth is not discovered early and managed effectively. It can be caused or exacerbated by more than 700 medications, both over-the-counter and prescription. Patients with certain health conditions or medical treatments, such as Sjögren’s disease or head and neck cancer therapy often experience Dry Mouth.

Despite being a common medical condition, the signs and symptoms may go unnoticed in a routine oral exam. It has been reported that the incidence of Dry Mouth in the general population is as high as 65 percent.

Source: ADA Science Institute, C. (2017). Oral Health Topics: Dry Mouth (Dry Mouth). JADA. Mouth.