Dry Mouth from Antihypertensives

Dry mouth, also known as xerostomia, frequently emerges as a side effect of various medications, notably antihypertensives. It's estimated that a significant portion of individuals on blood pressure-lowering drugs might experience this condition. The sensation of a perpetually dry mouth not only causes discomfort but can also adversely affect one's dental health. Persistent dry mouth may also affect strict adherence to the medications as patients seek some relief by reducing the amount of medication they take. Recognizing the underlying reasons for this occurrence and finding effective ways to mitigate it are crucial for those affected.

Understanding Antihypertensives and Dry Mouth

Popular Types of Antihypertensive

Antihypertensive medications, including ACE inhibitors like lisinopril and ARBs such as losartan, are commonly prescribed to manage high blood pressure. These medications can lead to dry mouth as a side effect. Other common antihypertensives like beta-blockers metoprolol, amlodipine, and hydrochlorothiazide may also cause dry mouth.

Why Antihypertensive Can Cause Dry Mouth

Antihypertensives may alter the function of muscarinic receptors, which are integral to the process of saliva secretion. Consequently, patients might notice symptoms linked to dry mouth, including difficulties in swallowing, a constant sore throat, and adverse effects on their oral health. This reaction is comparable to the dry mouth effects observed with medications like antidepressants, contributing broadly to the phenomenon of medication-induced xerostomia.

How Aquoral Treats Dry Mouth

Aquoral Protective Oral Spray is specially formulated to provide lasting protection against dry mouth symptoms caused by antihypertensives. By forming a protective film over the whole of the mucous membranes of the mouth,

Aquoral helps maintain oral moisture, offering relief from the discomfort such as with dry mouth caused by zoloft and other antidepressant-related dry mouth conditions.

The Science Behind Aquoral

In addition to its efficacy in combating dryness related to antidepressant use, Aquoral has shown promise in addressing similar symptoms in patients on antihypertensive medication. Many antihypertensive drugs, essential for controlling high blood pressure, can inadvertently decrease saliva production, leading to a condition known as "antihypertensive xerostomia." Aquoral's hydrating action aims to directly counters this side effect by mimicking natural saliva's lubricating and protective properties. This dual-action approach not only alleviates discomfort but also significantly improves the oral health quality of patients managing hypertension, ensuring that their vital medication does not compromise their oral health.

Understanding the Long-Term Effects of Dry Mouth

Unchecked, dry mouth can lead to severe dental health issues, including tooth decay, gum disease, and mouth infections.

It's crucial for patients experiencing dry mouth from antidepressants to seek treatment to mitigate these risks and preserve their oral health over the long term.

Seeking Treatment and Getting Help

Taking action and using Aquoral can greatly improve your life if you're dealing with dry mouth from antidepressants. Aquoral not only relieves immediate discomfort but also protects your dental health from issues like tooth decay and gum disease. By incorporating Aquoral into your daily routine, you're treating dry mouth and preserving your oral health, making eating, speaking, sleeping, swallowing, and smiling easier. Don't let medication-induced dry mouth affect your comfort. Try Aquoral for the relief and protection your mouth needs.

How to Seek Treatment with Aquoral

If you find yourself suffering from dry mouth as a side effect of antihypertensive drugs, relief is closer than you might think. Aquoral Protective Oral Spray is available by prescription, designed to combat the dry mouth associated with medication use. We encourage patients to reach out and discuss the advantages of incorporating Aquoral into their treatment plan. Our team is ready to assist you in understanding how Aquoral can alleviate the discomfort caused by dry mouth and help protect your oral health for the long term. Don't hesitate to take the first step towards a more comfortable and confident life with Aquoral.

Aquoral is committed to improving the quality of life for those dealing with the side effects of necessary medication. Contact us today to learn more about how Aquoral can support your oral health during antidepressant treatment.

Relief From Antihypertensives Xerostomia - Aquoral is:


Lipid-based spray lubricates and provides a protective shield that helps the oral mucosa retain moisture


Helps prevent mucosal damage & tooth decay while improving the ability to chew, taste, swallow, and speak

Fast & Long-lasting

Two quick sprays provide rapid relief that lasts for 4 to 6 hours, and reduces the need for frequent dosing

Easy to Use

Small size fits in a pocket or purse; no need for mixing or frequent rinsing as with water-based formulations

best mouth spray for dry mouth
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Convenient Packaging

Over-the-counter Dry Mouth products are often sold in large bottles due to the frequency of use. Prescription supersaturated calcium phosphate rinses come in foil packets which need to be mixed in a large quantity of water before use.

Aquoral comes in two convenient 10 mL spray bottles that easily fit in a pocket, purse, or on a night table.

No Rinse and Repeat

Many non-prescription Dry Mouth treatments and prescription supersaturated calcium phosphate rinses require rinsing and spitting out and should not be swallowed.

Aquoral is a discreet, easy-to-use spray.


Aquoral’s formulation provides long-lasting relief. Finally, a solution that lubricates AND forms a protective layer that keeps moisture in the oral cavity.

Delivering sustainable relief for up to 6 hours.

Provides Relief

Most saliva substitutes hydrate and lubricate the oral mucosa providing temporary relief of Dry Mouth.

Aquoral’s OGT formulation creates a protective shield which, when used alone or combined with other Dry Mouth treatments, can lock in moisture, and enhance effectiveness.

What is Dry Mouth?

Dry Mouth is a more serious medical condition than its name would suggest. In most cases, patients’ daily lives and oral health can be significantly compromised if their Dry Mouth is not discovered early and managed effectively. It can be caused or exacerbated by more than 700 medications, both over-the-counter and prescription. Patients with certain health conditions or medical treatments, such as Sjögren’s disease or head and neck cancer therapy often experience Dry Mouth.

Despite being a common medical condition, the signs and symptoms may go unnoticed in a routine oral exam. It has been reported that the incidence of Dry Mouth in the general population is as high as 65 percent.

Source: ADA Science Institute, C. (2017). Oral Health Topics: Dry Mouth (Dry Mouth). JADA. Mouth.